Richard A. Gemeinhart
Professor, College of Pharmacy - Pharmaceutical Sciences
Professor, Colleges of Engineering and Medicine - Biomedical Engineering
Professor, College of Engineering - Chemical Engineering
Professor, College of Medicine - Ophthalmology & Visual Sciences
Associate Vice Chancellor for Research, Office of the Vice Chancellor for Research
Research Integrity Officer, Office of the Vice Chancellor for Research
Director of Graduate Studies, Biopharmaceutical Sciences, College of Pharmacy - Pharmaceutical Sciences
Pharmaceutics and Drug Delivery Concentration Coordinator, College of Pharmacy - Pharmaceutical Sciences
Contact
Address:
833 South Wood Street (MC 781), 357 College of Pharmacy Building, Chicago, IL
Office Phone:
Email:
Related Sites:
About Heading link
Research Interests:
Prof. Gemeinhart’s laboratory focuses on understanding the stability, assembly, disassembly, and impact of biomaterials used for drug delivery focusing on polymeric drug delivery systems capable of delivering small molecules and biomacromolecules.
Teaching and Supervision Heading link
PSCI Ph.D. Thesis Research (PSCI 599), 8/26/2024 – 12/6/2024
PhD Thesis Research (BPS 599), 8/26/2024 – 12/6/2024
PSCI Ph.D. Thesis Research (PSCI 599), 6/10/2024 – 8/2/2024
PSCI Ph.D. Thesis Research (PSCI 599), 1/8/2024 – 4/26/2024
Pharmaceutics & Drug Delivery (PSCI 510), 1/8/2024 – 4/26/2024
PhD Thesis Research (BPS 599), 1/8/2024 – 4/26/2024
PSCI Ph.D. Thesis Research (PSCI 599), 8/21/2023 – 12/1/2023
PhD Thesis Research (BPS 599), 8/21/2023 – 12/1/2023
PSCI Ph.D. Thesis Research (PSCI 599), 6/12/2023 – 8/4/2023
Selected Grants
Novel Injectable Nanocrystal Drug to Treat Acute Respiratory Distress Syndrome (ARDS), University of Illinois at Chicago Discovery Partners Institute., 8/16/2019 - 6/1/2021, Obligated Amount: $100000; Anticipated Amount: $100000
A Novel nanoparticle Delivery System of miRNAs for Orthodontic Purposes, American Association of Orthodontists Foundation., 7/1/2019 - 11/15/2022, Obligated Amount: $30000; Anticipated Amount: $30000
Selected Publications
★ Andrianopoulou, Angeliki, Sokolowski, Karol, Wenzler, Eric, Bulman, Zackery P, Gemeinhart, Richard A. (2024). Assessment of antibiotic release and antibacterial efficacy from pendant glutathione hydrogels using ex vivo porcine skin. Journal of Controlled Release, 365, 936-949. doi:10.1016/j.jconrel.2023.12.008.
★ Dial, Catherine F, Gemeinhart, Richard. (2022). Biophysical characterization of interactions between serum albumin and block copolymers micelles. ACS Biomaterials Science and Engineering, ASAP. doi:10.1021/acsbiomaterials.2c00016.
★ Sokolowski, Karol, Pham, Hai M, Wenzler, Eric, Gemeinhart, Richard A. (2021). Glutathione-Conjugated Hydrogels: Flexible Vehicles for Personalized Treatment of Bacterial Infections. Pharmaceutical Research, 38, (7), 1247-1261. doi:10.1007/s11095-021-03057-1.
★ Langridge, Timothy D, Gemeinhart, Richard A. (2020). Toward understanding polymer micelle stability: Density ultracentrifugation offers insight into polymer micelle stability in human fluids.. J Control Release, 319, 157-167. doi:10.1016/j.jconrel.2019.12.038.
Liu, Y, Zhang, Y, Chen, SN, Friesen, JB, Nikolić, D, Choules, MP, McAlpine, JB, Lankin, DC, Gemeinhart, RA, Pauli, GF. (2018). The influence of natural deep eutectic solvents on bioactive natural products: studying interactions between a hydrogel model and Schisandra chinensis metabolites. Fitoterapia, 127, 212-219. doi:10.1016/j.fitote.2018.02.024.
★ Zhang, Y, Buhrman, JS, Liu, Y, Rayahin, JE, Gemeinhart, RA. (2016). Reducible Micelleplexes are Stable Systems for Anti-miRNA Delivery in Cerebrospinal Fluid. Molecular Pharmaceutics, 13, (6), 1791-1799. doi:10.1021/acs.molpharmaceut.5b00933.
★ Rayahin, JE, Buhrman, JS, Zhang, Y, Koh, TJ, Gemeinhart, RA. (2015). High and Low Molecular Weight Hyaluronic Acid Differentially Influence Macrophage Activation. ACS Biomaterials Science and Engineering, 1, (7), 481-493. doi:10.1021/acsbiomaterials.5b00181.
★ Zhang, Y, Liu, Y, Sen, S, Král, P, Gemeinhart, RA. (2015). Charged group surface accessibility determines micelleplexes formation and cellular interaction. Nanoscale, 7, (17), 7559-7564. doi:10.1039/c5nr00095e.
★ Rayahin, JE, Buhrman, JS, Gemeinhart, RA. (2014). Melittin-glutathione S-transferase fusion protein exhibits anti-inflammatory properties and minimal toxicity. European Journal of Pharmaceutical Sciences, 65, 112-121. doi:10.1016/j.ejps.2014.09.012.
Notable Honors
2019, Graduate Mentoring Award, University of Illinois at Chicago
Education
Degrees:
Ph.D, Purdue University, United States, 1999
B.S.E, Purdue University, United States, 1994
Postgraduate Training:
Postdoctoral, Cornell University, United States, 2001
Selected Presentations
Andrianopoulou, Angeliki, Sokolowski, Karol, Bulman, ZP, Wenzler, ER, Gemeinhart, Richard. (2022 July 19). Versatile, topical antibiotic delivery with glutathione-conjugated hydrogels. nternational Symposium on Controlled Release of Bioactive Materials. Montreal, ON.
Sokolowski, Karol, Smith, Nicholas, Bulman, Zackery, Wenzler, Eric, Gemeinhart, Richard. (2021 May 26). Evaluating Glutathione-conjugated Hydrogels as Localized Antibiotic Delivery Vehicles for Treatment of Bacterial Infections. International Society for Anti-Infective Pharmacology Annual Meeting.